Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 1545
Gene Symbol: CYP1B1
CYP1B1 		0.220 Biomarker disease RGD Cytochrome P450 1B1 expression in rat esophageal tumorigenesis promoted by gastric and duodenal reflux. 18618592 2009
Entrez Id: 3868
Gene Symbol: KRT16
KRT16 		0.200 Biomarker disease RGD Identification of cytokeratin subspecies altered in rat experimental esophageal tumors by subtractive cloning. 8950218 1996
Entrez Id: 51741
Gene Symbol: WWOX
WWOX 		0.530 SusceptibilityMutation disease ORPHANET The hypermethylation of promoter and exon1 of WWOX was found to be occurred in dysplastic tissues and the methylation frequency of WWOX in ESCC tumor tissues was significantly higher than that in corresponding normal tissues and was associated with UGIC family history. 22213016 2013
Entrez Id: 51741
Gene Symbol: WWOX
WWOX 		0.530 SusceptibilityMutation disease ORPHANET Genetic alterations of the tumor suppressor gene WWOX in esophageal squamous cell carcinoma. 11956080 2002
Entrez Id: 7048
Gene Symbol: TGFBR2
TGFBR2 		0.320 GeneticVariation disease ORPHANET These results are consistent with our previous findings in gastric cancer and support the hypothesis that genetic variants in TGFB1 and TGFBR2 may modulate the risk of ESCC. 17680270 2008
Entrez Id: 6049
Gene Symbol: RNF6
RNF6 		0.310 GeneticVariation disease ORPHANET Identification of multiple somatic mutations in RNF6 suggests that RNF6 is a potential tumor suppressor gene involved in the pathogenesis of ESCC. 12154016 2002
Entrez Id: 9940
Gene Symbol: DLEC1
DLEC1 		0.300 GeneticVariation disease ORPHANET Molecular cloning of a candidate tumor suppressor gene, DLC1, from chromosome 3p21.3. 10213508 1999
Entrez Id: 51196
Gene Symbol: PLCE1
PLCE1 		0.500 GeneticVariation disease GWASCAT Joint analysis of three genome-wide association studies of esophageal squamous cell carcinoma in Chinese populations. 25129146 2014
Entrez Id: 482
Gene Symbol: ATP1B2
ATP1B2 		0.400 GeneticVariation disease GWASCAT Joint analysis of three genome-wide association studies of esophageal squamous cell carcinoma in Chinese populations. 25129146 2014
Entrez Id: 340061
Gene Symbol: STING1
STING1 		0.400 GeneticVariation disease GWASCAT Joint analysis of three genome-wide association studies of esophageal squamous cell carcinoma in Chinese populations. 25129146 2014
Entrez Id: 100048912
Gene Symbol: CDKN2B-AS1
CDKN2B-AS1 		0.160 GeneticVariation disease GWASCAT Joint analysis of three genome-wide association studies of esophageal squamous cell carcinoma in Chinese populations. 25129146 2014
Entrez Id: 861
Gene Symbol: RUNX1
RUNX1 		0.140 GeneticVariation disease GWASCAT Joint analysis of three genome-wide association studies of esophageal squamous cell carcinoma in Chinese populations. 25129146 2014
Entrez Id: 7494
Gene Symbol: XBP1
XBP1 		0.110 GeneticVariation disease GWASCAT Joint analysis of three genome-wide association studies of esophageal squamous cell carcinoma in Chinese populations. 25129146 2014
Entrez Id: 5144
Gene Symbol: PDE4D
PDE4D 		0.100 GeneticVariation disease GWASCAT Joint analysis of three genome-wide association studies of esophageal squamous cell carcinoma in Chinese populations. 25129146 2014
Entrez Id: 130540
Gene Symbol: FLACC1
FLACC1 		0.100 GeneticVariation disease GWASCAT Joint analysis of three genome-wide association studies of esophageal squamous cell carcinoma in Chinese populations. 25129146 2014
Entrez Id: 1956
Gene Symbol: EGFR
EGFR 		0.700 CausalMutation disease CGI
Entrez Id: 7403
Gene Symbol: KDM6A
KDM6A 		0.520 CausalMutation disease CGI
Entrez Id: 7403
Gene Symbol: KDM6A
KDM6A 		0.520 GenomicAlterations disease CGI
Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1 		0.500 CausalMutation disease CGI
Entrez Id: 7157
Gene Symbol: TP53
TP53 		0.600 Biomarker disease CTD_mouse Zinc deficiency potentiates induction and progression of lingual and esophageal tumors in p53-deficient mice. 16543248 2006
Entrez Id: 1956
Gene Symbol: EGFR
EGFR 		0.700 Biomarker disease CTD_human Prognosis of esophageal squamous cell carcinoma in patients positive for human epidermal growth factor receptor family can be improved by initial chemotherapy with docetaxel, fluorouracil, and cisplatin. 21947696 2012
Entrez Id: 7157
Gene Symbol: TP53
TP53 		0.600 Biomarker disease CTD_human Genetic landscape of esophageal squamous cell carcinoma. 25151357 2014
Entrez Id: 51741
Gene Symbol: WWOX
WWOX 		0.530 Biomarker disease CTD_human Towards a systematic analysis of human short-chain dehydrogenases/reductases (SDR): Ligand identification and structure-activity relationships. 25526675 2015
Entrez Id: 7403
Gene Symbol: KDM6A
KDM6A 		0.520 Biomarker disease CTD_human Genetic landscape of esophageal squamous cell carcinoma. 25151357 2014
Entrez Id: 51196
Gene Symbol: PLCE1
PLCE1 		0.500 Biomarker disease CTD_human PLCE1 and C20orf54 have important biological implications for both ESCC and GCA. 20729853 2010